Jumat, 18 Maret 2011

Nuclear medicine

Nuclear medicine is a branch or specialty of medicine and medical imagingthat uses radionuclides and relies on the process of radioactive decay in the diagnosis and treatment of disease.


In nuclear medicine procedures, elemental radionuclides are combined with other elements to form chemical compounds, or else combined with existingpharmaceutical compounds, to form radiopharmaceuticals. These radiopharmaceuticals, once administered to the patient, can localize to specific organs or cellular receptors. This property of radiopharmaceuticals allows nuclear medicine the ability to image the extent of a disease-process in the body, based on the cellular function and physiology, rather than relying on physical changes in the tissue anatomy. In some diseases nuclear medicine studies can identify medical problems at an earlier stage than other diagnostic tests.

Treatment of diseased tissue, based on metabolism or uptake or binding of a particular ligand, may also be accomplished, similar to other areas of pharmacology. However, the treatment effects of radiopharmaceuticals rely on the tissue-destructive power of short-range ionizing radiation.


Further reading

  • Mas JC: A Patient's Guide to Nuclear Medicine Procedures: English-Spanish. Society of Nuclear Medicine, 2008. ISBN 978-0972647892
  • Taylor A, Schuster DM, Naomi Alazraki N: A Clinicians' Guide to Nuclear Medicine, 2nd edition. Society of Nuclear Medicine, 2000. ISBN 978-0932004727
  • Mark J. Shumate MJ, Kooby DA, Alazraki NP: A Clinician's Guide to Nuclear Oncology: Practical Molecular Imaging and Radionuclide Therapies. Society of Nuclear Medicine, January 2007. ISBN 978-0972647885
  • Ell P, Gambhir S: Nuclear Medicine in Clinical Diagnosis and Treatment. Churchill Livingstone, 2004. (1950 pages) ISBN 978-0443073120
External links
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